Badwater 135
From the race director: "The Badwater 135 is the most demanding and extreme running race offered anywhere on the planet. The start line is at Badwater, Death Valley, which marks the lowest elevation in North America at 280’ (85m) below sea level. The race finishes at Whitney Portal at 8,300’ (2530m). The Badwater 135 course covers three mountain ranges for a total of 14,600’ (4450m) of cumulative vertical ascent and 6,100’ (1859m) of cumulative descent. Whitney Portal is the trailhead to the Mt. Whitney summit, the highest point in the contiguous United States. Competitors travel through places or landmarks with names like Mushroom Rock, Furnace Creek, Salt Creek, Devil’s Cornfield, Devil’s Golf Course, Stovepipe Wells, Panamint Springs, Keeler, Alabama Hills, and Lone Pine."